Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human FBXO43
Specificity
This antibody detects endogenous levels of FBXO43 at Human,Rat
Gene Name
FBXO43 EMI2
Protein Name
F-box only protein 43 (Endogenous meiotic inhibitor 2)
Other Name
Species
Human
Gene ID
286151
Uniprot
Q4G163,
Species.1
Mouse
Gene ID.1
Uniprot.1
Q8CDI2,
Species.2
Rat
Gene ID.2
315034
Uniprot.2
Q66H04
Cellular Localization
Tissue Expression
Signaling_pathway
Research Areas
Function
Required to establish and maintain the arrest of oocytes at the second meiotic metaphase until fertilization. Probably acts by inhibiting the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase. Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation (Probable).