Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human FEZ1
Specificity
This antibody detects endogenous levels of FEZ1 at Human, Mouse,Rat
Gene Name
FEZ1
Protein Name
Fasciculation and elongation protein zeta-1 (Zygin I) (Zygin-1)
Other Name
Species
Human
Gene ID
9638
Uniprot
Q99689,
Species.1
Mouse
Gene ID.1
235180
Uniprot.1
Q8K0X8,
Species.2
Rat
Gene ID.2
81730
Uniprot.2
P97577
Cellular Localization
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cell membrane . Colocalizes with both, alpha- and gamma-tubulin. Translocated from the plasma membrane to the cytoplasm by activation of the PKC zeta (By similarity). .
Tissue Expression
Mainly expressed in brain.
Signaling_pathway
Research Areas
Function
May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules.