FLIP1 Polyclonal Antibody
Product details
Background:
function:By acting through a filamin-A/F-actin axis, it controls the start of neocortical cell migration from the ventricular zone. May be able to induce the degradation of filamin-A., similarity:Belongs to the FILIP1 family., subunit:Interacts with FLNA., tissue specificity:Moderately expressed in adult heart and brain. Weakly expressed in lung, skeletal muscle, ovary, testis, kidney, and fetal brain, and hardly detectable in liver, pancreas, spleen, and fetal liver. Within brain, moderate expression is found in amygdala and caudate nucleus.,
Specifications
| Size | 50μL/100μL |
| Target | FLIP1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 133kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | FLIP1 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | FILIP1 KIAA1275 |
| Protein Name | Filamin-A-interacting protein 1 (FILIP) |
| Other Name | |
| Species | Human |
| Gene ID | 27145 |
| Uniprot | Q7Z7B0, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q9CS72, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | Q8K4T4 |
| Cellular Localization | Cytoplasm, cytoskeleton . |
| Tissue Expression | Moderately expressed in adult heart and brain. Weakly expressed in lung, skeletal muscle, ovary, testis, kidney, and fetal brain, and hardly detectable in liver, pancreas, spleen, and fetal liver. Within brain, moderate expression is found in amygdala and caudate nucleus. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:By acting through a filamin-A/F-actin axis, it controls the start of neocortical cell migration from the ventricular zone. May be able to induce the degradation of filamin-A.,similarity:Belongs to the FILIP1 family.,subunit:Interacts with FLNA.,tissue specificity:Moderately expressed in adult heart and brain. Weakly expressed in lung, skeletal muscle, ovary, testis, kidney, and fetal brain, and hardly detectable in liver, pancreas, spleen, and fetal liver. Within brain, moderate expression is found in amygdala and caudate nucleus., |
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