Product details
Background:
FNTA rabbit pAb
Ucallm_WP7274-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | FNTA |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 42kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human FNTA |
| Specificity | This antibody detects endogenous levels of FNTA at Human, Mouse,Rat |
| Gene Name | FNTA |
| Protein Name | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (CAAX farnesyltransferase subunit alpha) (FTase-alpha) (Ras proteins prenyltransferase subunit alpha) (Type I protein geranyl-geranyltransferase subunit alpha) (GGTase-I-alpha) |
| Other Name | |
| Species | Human |
| Gene ID | 2339 |
| Uniprot | P49354, |
| Species.1 | Mouse |
| Gene ID.1 | 14272 |
| Uniprot.1 | Q61239, |
| Species.2 | Rat |
| Gene ID.2 | 25318 |
| Uniprot.2 | Q04631 |
| Cellular Localization | |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation. |
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