Price range: $268.00 through $328.00
Background:
Members of the winged-helix/forkhead family of transcription factors, such as FOXN4, are characterized by a 110-amino acid DNA-binding domain that can fold into a variant of the helix-turn-helix motif consisting of 3 alpha helices flanked by 2 large loops or wings. These transcription factors are involved in a variety of biologic processes as key regulators in development and metabolism (Li et al., 2004 [PubMed 15363391]).[supplied by OMIM, Mar 2008],
| Size | 50μL/100μL |
| Target | FoxN4 |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 50kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human FOXN4. AA range:411-460 |
| Specificity | FoxN4 Polyclonal Antibody detects endogenous levels of FoxN4 protein. |
| Gene Name | FOXN4 |
| Protein Name | Forkhead box protein N4 |
| Other Name | FOXN4; / Forkhead box protein N4 |
| Species | Human |
| Gene ID | 121643 |
| Uniprot | Q96NZ1, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q8K3Q3 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | Brain,Clones donated by RIKEN, |
| Signaling_pathway | |
| Research Areas | |
| Function | similarity:Contains 1 fork-head DNA-binding domain., |
