FTSJD2 rabbit pAb
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | CMTR1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 92kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human FTSJD2 |
| Specificity | This antibody detects endogenous levels of FTSJD2 at Human, Mouse,Rat |
| Gene Name | FTSJD2 KIAA0082 MTR1 |
| Protein Name | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (Cap1 2'O-ribose methyltransferase 1) (MTr1) (hMTr1) (FtsJ methyltransferase domain-containing protein 2) (Interferon-stimulated gene 95 kDa protein) (ISG95) |
| Other Name | |
| Species | Human |
| Gene ID | 23070 |
| Uniprot | Q8N1G2, |
| Species.1 | Mouse |
| Gene ID.1 | 74157 |
| Uniprot.1 | Q9DBC3, |
| Species.2 | Rat |
| Gene ID.2 | 309656 |
| Uniprot.2 | Q5U2Z5 |
| Cellular Localization | Nucleus . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway. |
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