SKU: WP8926 Categories: ,

FTSJD2 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP8926-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetCMTR1
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)92kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human FTSJD2
SpecificityThis antibody detects endogenous levels of FTSJD2 at Human, Mouse,Rat
Gene NameFTSJD2 KIAA0082 MTR1
Protein NameCap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (Cap1 2'O-ribose methyltransferase 1) (MTr1) (hMTr1) (FtsJ methyltransferase domain-containing protein 2) (Interferon-stimulated gene 95 kDa protein) (ISG95)
Other Name
SpeciesHuman
Gene ID23070
UniprotQ8N1G2,
Species.1Mouse
Gene ID.174157
Uniprot.1Q9DBC3,
Species.2Rat
Gene ID.2309656
Uniprot.2Q5U2Z5
Cellular LocalizationNucleus .
Tissue Expression
Signaling_pathway
Research Areas
FunctionS-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.
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