Fucokinase Monoclonal Antibody
Ucallm_WM0204-50
Price range: $268.00 through $328.00
Product details
Background:
fucokinase(FUK) Homo sapiens The protein encoded by this gene belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis. While several transcript variants may exist for this gene, the full-length nature of only one has been described to date. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | Fucokinase |
| Reactivity | Human, Mouse, Rat, Monkey |
| Applications | WB, FC, ELISA |
| MW(Calculated) | 118kD |
| MW(Observed) | |
| Host Species | Mouse |
| Isotype | |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; Flow Cyt 1:200-1:400; ELISA 1:10000; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | Affinity purification |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | 12C2 |
| Immunogen | Purified recombinant fragment of human Fucokinase expressed in E. Coli. |
| Specificity | Fucokinase Monoclonal Antibody detects endogenous levels of Fucokinase protein. |
| Gene Name | FUK |
| Protein Name | L-fucose kinase |
| Other Name | FUK; / L-fucose kinase; / Fucokinase |
| Species | Human |
| Gene ID | 197258 |
| Uniprot | Q8N0W3 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | cytoplasm,cytosol, |
| Tissue Expression | Expressed in fibroblasts. |
| Signaling_pathway | |
| Research Areas | >>Fructose and mannose metabolism; / >>Amino sugar and nucleotide sugar metabolism; / >>Metabolic pathways; / >>Biosynthesis of nucleotide sugars |
| Function | Catalytic activity:ATP + L-fucose = ADP + beta-L-fucose 1-phosphate.,Function:Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides.,similarity:Belongs to the GHMP kinase family., |
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