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FXYD3 rabbit pAb
Ucallm_WP16271-50
Price range: $268.00 through $328.00
Product details
Background:
This gene belongs to a small family of FXYD-domain containing regulators of Na+/K+ ATPases which share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD, and containing 7 invariant and 6 highly conserved amino acids. This gene encodes a cell membrane protein that may regulate the function of ion-pumps and ion-channels. This gene may also play a role in tumor progression. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2008],
Specifications
| Size | 50μL/100μL |
| Target | FXYD3 |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC, IF |
| MW(Calculated) | 10kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:50-200; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human FXYD3 AA range: 15-65 |
| Specificity | This antibody detects endogenous levels of FXYD3 at Human/Mouse/Rat |
| Gene Name | FXYD3 MAT8 PLML |
| Protein Name | FXYD3 |
| Other Name | |
| Species | Human |
| Gene ID | 5349 |
| Uniprot | Q14802, |
| Species.1 | Mouse |
| Gene ID.1 | 17178 |
| Uniprot.1 | Q61835, |
| Species.2 | Rat |
| Gene ID.2 | 116831 |
| Uniprot.2 | P59645 |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein . |
| Tissue Expression | Isoform 1: Expressed mainly in differentiated cells (at protein level). Isoform 2: Expressed mainly in undifferentiated cells (at protein level). |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes. May be a modulator capable of activating endogenous oocyte channels.,miscellaneous:Marker of a cell type preferentially transformed by neu or ras oncoprotein.,similarity:Belongs to the FXYD family.,tissue specificity:Expressed in a subset of human breast tumors., |
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