Product details
Background:
Galectin 10 rabbit pAb
Ucallm_WP6915-50
Price range: $268.00 through $328.00
Specifications
| Target | CLC |
| Reactivity | Human |
| Applications | WB |
| MW(Calculated) | 16kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Modification | |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Purity | |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human Galectin 10 |
| Sequence | |
| Specificity | This antibody detects endogenous levels of Galectin 10 at Human |
| Gene Name | CLC |
| Protein Name | Eosinophil lysophospholipase (Charcot-Leyden crystal protein) (CLC) (Galectin-10) (Gal-10) (Lysolecithin acylhydrolase) |
| Other Name | |
| Species | Human |
| Gene ID-1 | 1178 |
| Uniprot | Q05315, |
| Species.1 | Mouse |
| Gene ID-2 | |
| Uniprot.1 | P97400 |
| Species.2 | |
| Gene ID-3 | |
| Uniprot.2 | |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Background | |
| Cellular Localization | Cytoplasm, cytosol . Cytoplasmic granule . Localized in granules from where it may be secreted or transported to other locations in the cell. |
| Tissue Expression | Expressed abundantly in the bone marrow. Expressed exclusively by eosinophils and basophils. Not detected in monocytes and neutrophils. Expressed in CD25-positive regulatory T-cells (Treg) (at protein level). Found in intestinal tissue from patients with Celiac disease, expression is directly related to the histological grade of mucosal damage and to the number of eosinophils found in the duodenal lesion (at protein level). Found in sputum of patients with eosinophilic inflammatory diseases such as asthma (at protein level). |
| Signaling_pathway | |
| Research Areas | |
| Function | Regulates immune responses through the recognition of cell-surface glycans. Essential for the anergy and suppressive function of CD25-positive regulatory T-cells (Treg). |
| RRID |
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