Price range: $268.00 through $328.00
Background:
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium. A duplicate copy of this gene (GeneID:653499) is found adjacent to, but on the opposite strand on chromosome 19. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | Galectin-7 |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC, IF, WB, ELISA |
| MW(Calculated) | 16kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; IHC 1:100-1:300; ELISA 1:5000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human LEG7. AA range:41-90 |
| Specificity | Galectin-7 Polyclonal Antibody detects endogenous levels of Galectin-7 protein. |
| Gene Name | LGALS7 |
| Protein Name | Galectin-7 |
| Other Name | LGALS7; / PIG1; / LGALS7B; / Galectin-7; / Gal-7; / HKL-14; / PI7; / p53-induced gene 1 protein |
| Species | Human |
| Gene ID | 3963;653499 |
| Uniprot | P47929, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | O54974, |
| Species.2 | Rat |
| Gene ID.2 | 29518 |
| Uniprot.2 | P97590 |
| Cellular Localization | Cytoplasm . Nucleus . Secreted . May be secreted by a non-classical secretory pathway. |
| Tissue Expression | Mainly expressed in stratified squamous epithelium. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release.,induction:By p53.,online information:Galectin-7,similarity:Contains 1 galectin domain.,subcellular location:May be secreted by a non-classical secretory pathway.,subunit:Monomer.,tissue specificity:Mainly in stratified squamous epithelium., |
