SKU: WP12412 Categories: ,

Galectin-8 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP12412-100
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Product details

Background:

This gene encodes a member of the galectin family. Galectins are beta-galactoside-binding animal lectins with conserved carbohydrate recognition domains. The galectins have been implicated in many essential functions including development, differentiation, cell-cell adhesion, cell-matrix interaction, growth regulation, apoptosis, and RNA splicing. This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetGalectin-8
ReactivityHuman, Mouse
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)36kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC: 1:100-300; ELISA 1:20000; IF 1:100-300; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human LEG8. AA range:61-110
SpecificityGalectin-8 Polyclonal Antibody detects endogenous levels of Galectin-8 protein.
Gene NameLGALS8
Protein NameGalectin-8
Other NameLGALS8; / Galectin-8; / Gal-8; / Po66 carbohydrate-binding protein; / Po66-CBP; / Prostate carcinoma tumor antigen 1; / PCTA-1
SpeciesHuman
Gene ID3964
UniprotO00214,
Species.1Mouse
Gene ID.156048
Uniprot.1Q9JL15
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasmic vesicle . Cytoplasm, cytosol .
Tissue ExpressionUbiquitous. Selective expression by prostate carcinomas versus normal prostate and benign prostatic hypertrophy.
Signaling_pathway
Research Areas
FunctionDomain:Contains two homologous but distinct carbohydrate-binding domains.,online information:Galectin-8 C-terminal CRD,online information:Galectin-8 long isoform,similarity:Contains 2 galectin domains.,tissue specificity:Ubiquitous. Selective expression by prostate carcinomas versus normal prostate and benign prostatic hypertrophy.,
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