Price range: $268.00 through $328.00
Background:
This gene encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Thrombin, urokinase, plasmin and trypsin are among the proteases that this family member can inhibit. This gene is a susceptibility gene for chronic obstructive pulmonary disease and for emphysema. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],
| Size | 50μL/100μL |
| Target | GDN |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 43kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | GDN Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | SERPINE2 PI7 PN1 |
| Protein Name | Glia-derived nexin (GDN) (Peptidase inhibitor 7) (PI-7) (Protease nexin 1) (PN-1) (Protease nexin I) (Serpin E2) |
| Other Name | |
| Species | Human |
| Gene ID | 5270 |
| Uniprot | P07093, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q07235, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | P07092 |
| Cellular Localization | Secreted, extracellular space. |
| Tissue Expression | Hippocampus,Skin, |
| Signaling_pathway | Organismal Systems >> Immune system >> Complement and coagulation cascades |
| Research Areas | |
| Function | Function:Serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Promotes neurite extension by inhibiting thrombin. Binds heparin.,similarity:Belongs to the serpin family., |
