Price range: $268.00 through $328.00
Background:
The secretory protein encoded by this gene is produced in gastric surface mucous cells, where it can bind trefoil factor family peptide 1 or gastrokine-1. This gene may be a tumor suppressor gene, as its expression is markedly decreased in gastric cancer tissues. The encoded protein interacts with gastrokine-1 and regulates homeostasis of the gastric mucosa. [provided by RefSeq, Dec 2015],
| Size | 50μL/100μL |
| Target | GKN2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 20kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 30-110 |
| Specificity | GKN2 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | GKN2 BLOT GDDR TFIZ1 UNQ465/PRO813 |
| Protein Name | Gastrokine-2 (Blottin) (Down-regulated in gastric cancer) (Trefoil factor interactions(z) 1) |
| Other Name | |
| Species | Human |
| Gene ID | 200504 |
| Uniprot | Q86XP6, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q9CQS6, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | Q29TV8 |
| Cellular Localization | Secreted. |
| Tissue Expression | Expressed in gastric mucosa. |
| Signaling_pathway | |
| Research Areas | |
| Function | similarity:Contains 1 BRICHOS domain.,subunit:Interacts with TFF2 (By similarity). Heterodimer with TFF1; disulfide linked.,tissue specificity:Expressed in gastric mucosa., |
