Glycophorin A [ABT-GYPA] mouse mAb
Ucallm_WM1672-50
Price range: $268.00 through $328.00
Product details
Background:
Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. In addition to the M or N and S or s antigens that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, as well as Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | Glycophorin A |
| Reactivity | Human |
| Applications | IHC, ELISA |
| MW(Calculated) | 16kD |
| MW(Observed) | 37kD |
| Host Species | Mouse |
| Isotype | IgG1,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-400; ELISA 1:500-5000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RMM-GYPA |
| Immunogen | Synthesized peptide derived from human Glycophorin A，CD235a AA range: 1-100 |
| Specificity | The antibody can specifically recognize human Glycophorin A protein. |
| Gene Name | GYPA GPA |
| Protein Name | Glycophorin A，CD235a |
| Other Name | Glycophorin-A; / MN sialoglycoprotein; / PAS-2; / Sialoglycoprotein alpha; / CD antigen CD235a |
| Species | Human |
| Gene ID | 2993 |
| Uniprot | P02724 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Membranous |
| Tissue Expression | Blood,Bone marrow,Kidney,Liver,Lung,Miltenberger class V, |
| Signaling_pathway | Organismal Systems >> Immune system >> Hematopoietic cell lineage |
| Research Areas | >>Hematopoietic cell lineage; / >>Malaria |
| Function | Function:Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors and also binds influenza virus.,online information:Blood group antigen gene mutation database,polymorphism:Along with GYPB, GYPA is responsible for the MNS blood group system.,similarity:Belongs to the glycophorin A family., |
Please login to post questions
Related products
