Price range: $268.00 through $328.00
Background:
This gene encodes a member of the ARHGAP family of Rho/Rac/Cdc42-like GTPase activating proteins. The encoded protein interacts with the Ras-related protein Gem through its N-terminal domain. Separately, it interacts with RhoA through a RhoGAP domain, and stimulates RhoA-dependent GTPase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],
| Size | 50μL/100μL |
| Target | GMIP |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | |
| MW(Observed) | 105kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human GMIP AA range: 421-471 |
| Specificity | This antibody detects endogenous levels of GMIP at Human/Mouse |
| Gene Name | GMIP |
| Protein Name | GMIP |
| Other Name | GEM-interacting protein; / GMIP |
| Species | Human |
| Gene ID | 51291 |
| Uniprot | Q9P107, |
| Species.1 | Mouse |
| Gene ID.1 | 78816 |
| Uniprot.1 | Q6PGG2 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | intracellular,cytosol, |
| Tissue Expression | Brain,Leukemia,Platelet, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Stimulates, in vitro and in vivo, the GTPase activity of RhoA.,similarity:Contains 1 phorbol-ester/DAG-type zinc finger.,similarity:Contains 1 Rho-GAP domain.,subunit:Interacts with GEM through its N-terminal., |
