SKU: WP8709 Categories: ,

GNB2 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP8709-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetGNB2
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)37kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human GNB2
SpecificityThis antibody detects endogenous levels of GNB2 at Human, Mouse,Rat
Gene NameGNB2
Protein NameGuanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (G protein subunit beta-2) (Transducin beta chain 2)
Other Name
SpeciesHuman
Gene ID2783
UniprotP62879,
Species.1Mouse
Gene ID.114693
Uniprot.1P62880,
Species.2Rat
Gene ID.281667
Uniprot.2P54313
Cellular LocalizationCytoplasm, perinuclear region . Cell membrane .
Tissue ExpressionExpressed in all cardiac subcompartments and in the brain, with highest levels in the atrioventricular node and brain.
Signaling_pathwayOrganismal Systems >> Immune system >> Chemokine signaling pathway;Organismal Systems >> Endocrine system >> Relaxin signaling pathway;Organismal Systems >> Nervous system >> Glutamatergic synapse;Organismal Systems >> Nervous system >> Cholinergic synapse;Organismal Systems >> Nervous system >> Dopaminergic synapse;Human Diseases >> Cancer: overview >> Pathways in cancer;Environmental Information Processing >> Signal transduction >> Ras signaling pathway;Environmental Information Processing >> Signal transduction >> Apelin signaling pathway;Environmental Information Processing >> Signal transduction >> PI3K-Akt signaling pathway
Research Areas
FunctionGuanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
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