GNB4 rabbit pAb
Ucallm_WP7871-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | GNB4 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 37kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human GNB4 |
| Specificity | This antibody detects endogenous levels of GNB4 at Human, Mouse,Rat |
| Gene Name | GNB4 |
| Protein Name | Guanine nucleotide-binding protein subunit beta-4 (Transducin beta chain 4) |
| Other Name | |
| Species | Human |
| Gene ID | 59345 |
| Uniprot | Q9HAV0, |
| Species.1 | Mouse |
| Gene ID.1 | 14696 |
| Uniprot.1 | P29387, |
| Species.2 | Rat |
| Gene ID.2 | 294962 |
| Uniprot.2 | O35353 |
| Cellular Localization | |
| Tissue Expression | Strongly expressed in lung and placenta, whereas it is weakly expressed in brain and heart. Abundantly expressed in the axons and Schwann cells of peripheral nerves. |
| Signaling_pathway | Organismal Systems >> Immune system >> Chemokine signaling pathway;Organismal Systems >> Endocrine system >> Relaxin signaling pathway;Organismal Systems >> Nervous system >> Glutamatergic synapse;Organismal Systems >> Nervous system >> Cholinergic synapse;Organismal Systems >> Nervous system >> Dopaminergic synapse;Human Diseases >> Cancer: overview >> Pathways in cancer;Environmental Information Processing >> Signal transduction >> Ras signaling pathway;Environmental Information Processing >> Signal transduction >> Apelin signaling pathway;Environmental Information Processing >> Signal transduction >> PI3K-Akt signaling pathway |
| Research Areas | |
| Function | Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. |
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