U-Blot® Histone 1.0 Rabbit pAb
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Price range: $268.00 through $328.00
Product details
Background:Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-independent histone that is a member of the histone H1 family. [provided by RefSeq, Oct 2015],
Specifications
| Target | Histone 1.0 |
| Reactivity | Human,Rat,Mouse, |
| Application | WB,IHC,IF,ELISA |
| MW(Calculated) | |
| MW(Observed) | 28kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Modification | Unmodified |
| Modification site | |
| Recommended dilution ratio | WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Purity | |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Histone 1F0. AA range:71-120 |
| Sequence | |
| Specificity | Histone 1.0 Polyclonal Antibody detects endogenous levels of Histone 1.0 protein. |
| Gene name | H1F0 |
| Protein name | Histone H1.0 |
| Alternative name | H1F0;H1FV;Histone H1.0;Histone H1';Histone H1;0; |
| Organism-1 | Human |
| Gene ID‑1 | 3005 |
| SwissProt-1 | P07305 |
| Organism-2 | Mouse |
| Gene ID‑2 | |
| SwissProt-2 | P10922 |
| Organism-3 | |
| Gene ID‑3 | |
| SwissProt-3 | |
| Organism-4 | |
| Gene ID‑4 | |
| SwissProt-4 | |
| Cellular Localization | Nucleus . Chromosome . The RNA edited version has been localized to nuclear speckles. During mitosis, it appears in the vicinity of condensed chromosomes. |
| Unnamed: 38 | |
| Unnamed: 39 |
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