U-Blot® Histone H2A.X (Acetyl Lys5) Rabbit pAb

Price range: $288.00 through $368.00

SKU: WP0441-100
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Product details

Background:Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015],

Specifications

TargetHistone H2A.X
ReactivityHuman,Mouse,Rat
ApplicationWB
MW(Calculated)
MW(Observed)15kD
Host SpeciesRabbit
IsotypeIgG
ConjugateUnconjugated
ModificationAcetyl
Modification siteLys5
Recommended dilution ratioWB 1:1000-2000
FormulationPBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Source
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.
Purity
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
ClonalityPolyclonal
Clone Number
ImmunogenSynthetic Peptide of Histone H2A.X (Acetyl Lys5)
Sequence
SpecificityThe antibody detects endogenous Histone H2A.X (Acetyl Lys5) protein.
Gene nameH2AFX
Protein nameHistone H2A.x
Alternative nameH2AFX;H2AX;Histone H2A.x;H2a/x
Organism-1Human
Gene ID‑13014
SwissProt-1P16104
Organism-2Mouse
Gene ID‑215270
SwissProt-2P27661
Organism-3
Gene ID‑3
SwissProt-3
Organism-4
Gene ID‑4
SwissProt-4
Cellular LocalizationNucleus . Chromosome .
Unnamed: 38
Unnamed: 39
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