U-Blot® Histone H3 (citrulline R2) rabbit pAb
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Price range: $268.00 through $328.00
Product details
Background:Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015],
Specifications
| Target | Histone H3 |
| Reactivity | Human,Mouse,Rat |
| Application | WB |
| MW(Calculated) | 15kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Modification | Unmodified |
| Modification site | Arg2 |
| Recommended dilution ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Purity | |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human Histone H3 (citrulline R2) |
| Sequence | |
| Specificity | This antibody detects endogenous levels of Histone H3 (citrulline R2) at Human, Mouse,Rat |
| Gene name | HIST1H3A H3FA; HIST1H3B H3FL; HIST1H3C H3FC; HIST1H3D H3FB; HIST1H3E H3FD; HIST1H3F H3FI; HIST1H3G H3FH; HIST1H3H H3FK; HIST1H3I H3FF; HIST1H3J H3FJ |
| Protein name | Histone H3 (citrulline R2) |
| Alternative name | Histone H3.1;Histone H3/a;Histone H3/b;Histone H3/c;Histone H3/d;Histone H3/f;Histone H3/h;Histone H3/i;Histone H3/j;Histone H3/k;Histone H3/l; |
| Organism-1 | Human |
| Gene ID‑1 | 8350 |
| SwissProt-1 | P68431 |
| Organism-2 | Mouse |
| Gene ID‑2 | 319152 |
| SwissProt-2 | P68433 |
| Organism-3 | Rat |
| Gene ID‑3 | 291159 |
| SwissProt-3 | Q6LED0 |
| Organism-4 | |
| Gene ID‑4 | |
| SwissProt-4 | |
| Cellular Localization | Nucleus. Chromosome. |
| Unnamed: 38 | |
| Unnamed: 39 |
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