U-Blot® Histone H4 (Tri Methyl Lys79) Rabbit pAb
Product details
Background:Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33. [provided by RefSeq, Aug 2015],
Specifications
| Target | Histone H4 |
| Reactivity | Human,Mouse,Rat |
| Application | WB |
| MW(Calculated) | |
| MW(Observed) | 14kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Modification | Tri Methyl |
| Modification site | Lys79 |
| Recommended dilution ratio | WB 1:500-1000 |
| Formulation | PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol. |
| Source | |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen. |
| Purity | |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthetic Peptide of Histone H4 (Tri Methyl Lys79) |
| Sequence | |
| Specificity | The antibody detects endogenous Histone H4 (Tri Methyl Lys79) protein. |
| Gene name | HIST1H4A H4/A H4FA; HIST1H4B H4/I H4FI; HIST1H4C H4/G H4FG; HIST1H4D H4/B H4FB; HIST1H4E H4/J H4FJ; HIST1H4F H4/C H4FC; HIST1H4H H4/H H4FH; HIST1H4I H4/M H4FM; HIST1H4J H4/E H4FE; HIST1H4K H4/D H4FD; HIST1H4L H4/K H4FK; HIST2H4A H4/N H4F2 H4FN HIST2H4; HIST2H4B H4/O H4FO; HIST4H4 |
| Protein name | Histone H4 |
| Alternative name | H4K79ME3;HIST1H4A;H4/A;H4FA;HIST1H4B;H4/I;H4FI;HIST1H4C;H4/G;H4FG;HIST1H4D;H4/B;H4FB;HIST1H4E;H4/J;H4FJ;HIST1H4F;H4/C;H4FC;HIST1H4H;H4/H;H4FH;HIST1H4I;H4/M;H4FM;HIST1H4J;H4/E;H4FE;HIST1H4K;H4/D;H4FD;HIST1H4L;H4/K;H4FK;HIST2H4A;H4/N;H4F2;H4FN;HIST2H4;HIST2H4B;H4/O;H4FO;HIST4H4;Histone H4 |
| Organism-1 | Human |
| Gene ID‑1 | 121504;554313;8294;8359;8360;8361;8362;8363;8364;8365;8366;8367;8368;8370 |
| SwissProt-1 | P62805 |
| Organism-2 | Mouse |
| Gene ID‑2 | 100041230 |
| SwissProt-2 | P62806 |
| Organism-3 | Rat |
| Gene ID‑3 | 100360950 |
| SwissProt-3 | P62804 |
| Organism-4 | |
| Gene ID‑4 | |
| SwissProt-4 | |
| Cellular Localization | Nucleus. Chromosome. |
| Unnamed: 38 | |
| Unnamed: 39 |





