HLX1 Monoclonal Antibody
Product details
Background:
function:Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis., sequence caution:Translation N-terminally extended., similarity:Belongs to the H2.0 homeobox family., similarity:Contains 1 homeobox DNA-binding domain., tissue specificity:Low level in normal B and T-cells, high level in activated lymphocytes and monocytes. Also found in thymus, tonsil, bone marrow, developing vessels, and fetal brain.,
Specifications
| Size | 50μL/100μL |
| Target | HLX1 |
| Reactivity | Human, Mouse, Rat, Bovine, Dog, Pig |
| Applications | WB |
| MW(Calculated) | 51kD |
| MW(Observed) | |
| Host Species | Mouse |
| Isotype | |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:1000-1:2000; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | Affinity purification |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | 17E8 |
| Immunogen | Purified recombinant human HLX1 (C-terminus) protein fragments expressed in E.coli. |
| Specificity | HLX1 Monoclonal Antibody detects endogenous levels of HLX1 protein. |
| Gene Name | HLX |
| Protein Name | H2.0-like homeobox protein |
| Other Name | HLX; / HLX1; / H2.0-like homeobox protein; / Homeobox protein HB24; / Homeobox protein HLX1 |
| Species | Human |
| Gene ID | 3142 |
| Uniprot | Q14774, |
| Species.1 | Mouse |
| Gene ID.1 | 15284 |
| Uniprot.1 | Q61670, |
| Species.2 | Rat |
| Gene ID.2 | 364069 |
| Uniprot.2 | A0JPN1 |
| Cellular Localization | Nucleus . |
| Tissue Expression | Low level in normal B and T-cells, high level in activated lymphocytes and monocytes. Also found in thymus, tonsil, bone marrow, developing vessels, and fetal brain. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis.,sequence Caution:Translation N-terminally extended.,similarity:Belongs to the H2.0 homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,tissue specificity:Low level in normal B and T-cells, high level in activated lymphocytes and monocytes. Also found in thymus, tonsil, bone marrow, developing vessels, and fetal brain., |
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