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HOOK1 rabbit pAb
Ucallm_WP5047-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | HOOK1 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 80kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human HOOK1 AA range: 201-251 |
| Specificity | This antibody detects endogenous levels of human HOOK1 |
| Gene Name | HOOK1 |
| Protein Name | Protein Hook homolog 1 (h-hook1) (hHK1) |
| Other Name | |
| Species | Human |
| Gene ID | 51361 |
| Uniprot | Q9UJC3, |
| Species.1 | Mouse |
| Gene ID.1 | 77963 |
| Uniprot.1 | Q8BIL5 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . Cytoplasm, cytoskeleton . Localizes to punctate cytoplasmic foci which do not appear to overlap with early or late endosomes, the endoplasmic reticulum, multivesicular bodies (MVBs), lysosomes, or mitochondria (By similarity). Often found in close association with microtubules (By similarity). Does not associate with the Golgi complex. During spermiogenesis, it localizes to the manchette in spermatids from steps 8-10. It is also present between the microtubule manchette and the nucleus. During manchette elongation, it is preferentially localized to the nuclear ring of the manchette, whereas the strong localization to the manchette decreases. In more mature spermatids, while the manchette migrates posteriorly, it localizes to punctuates spots. At later stages of spermatid differentiation, the punctuate expression pattern is found at both the attachment site and the proximal end of the elongated manchette. In contrast, it is not present in mature spermatozoa (By similarity). . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function |
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