HoxA5 Polyclonal Antibody
Ucallm_WP12730-50
Price range: $268.00 through $328.00
Product details
Background:
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | HoxA5 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 40kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from the N-terminal region of human HoxA5. |
| Specificity | HoxA5 Polyclonal Antibody detects endogenous levels of HoxA5 protein. |
| Gene Name | HOXA5 |
| Protein Name | Homeobox protein Hox-A5 |
| Other Name | HOXA5; / HOX1C; / Homeobox protein Hox-A5; / Homeobox protein Hox-1C |
| Species | Human |
| Gene ID | 3202 |
| Uniprot | P20719, |
| Species.1 | Mouse |
| Gene ID.1 | 15402 |
| Uniprot.1 | P09021, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | P52949 |
| Cellular Localization | Nucleus. |
| Tissue Expression | Ovary, |
| Signaling_pathway | |
| Research Areas | |
| Function | developmental stage:Expressed during embryogenesis and in adult kidney.,Function:Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Also binds to its own promoter. Binds specifically to the motif 5'-CYYNATTA[TG]Y-3'.,similarity:Belongs to the Antp homeobox family.,similarity:Contains 1 homeobox DNA-binding domain., |
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