HoxB5 Polyclonal Antibody
Ucallm_WP12735-50
Price range: $268.00 through $328.00
Product details
Background:
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | HoxB5 |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 29kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human HoxB5. AA range:150-199 |
| Specificity | HoxB5 Polyclonal Antibody detects endogenous levels of HoxB5 protein. |
| Gene Name | HOXB5 |
| Protein Name | Homeobox protein Hox-B5 |
| Other Name | HOXB5; / HOX2A; / Homeobox protein Hox-B5; / Homeobox protein HHO.C10; / Homeobox protein Hox-2A; / Homeobox protein Hu-1 |
| Species | Human |
| Gene ID | 3215 |
| Uniprot | P09067, |
| Species.1 | Mouse |
| Gene ID.1 | 15413 |
| Uniprot.1 | P09079 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus. |
| Tissue Expression | Spinal cord. |
| Signaling_pathway | |
| Research Areas | |
| Function | developmental stage:Embryo.,Function:Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.,similarity:Belongs to the Antp homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,tissue specificity:Spinal cord., |
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