Name: HPK1 Polyclonal Antibody
SKU: WP12743
Price: 268 USD
Availability: InStock

HPK1 Polyclonal Antibody

Ucallm_WP12743-50

Price range: $268.00 through $328.00

Size

100μl

50μl

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SKU: WP12743-100

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Product details

Background:

catalytic activity:ATP + a protein = ADP + a phosphoprotein., cofactor:Magnesium., function:May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in hematopoietic lineage decisions and growth regulation., similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily., similarity:Contains 1 CNH domain., similarity:Contains 1 protein kinase domain., subunit:Interacts with MAP3K1., tissue specificity:Expressed primarily in hematopoietic organs, including bone marrow, spleen and thymus. Also expressed at very low levels in lung, kidney, mammary glands and small intestine.,

Specifications

Size	50μL/100μL
Target	HPK1
Reactivity	Human, Mouse
Applications	WB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)	91kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-1:2000; ELISA 1:10000; IF 1:50-200
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	The antiserum was produced against synthesized peptide derived from human MEKKK 1. AA range:371-420
Specificity	HPK1 Polyclonal Antibody detects endogenous levels of HPK1 protein.
Gene Name	MAP4K1
Protein Name	Mitogen-activated protein kinase kinase kinase kinase 1
Other Name	MAP4K1; / HPK1; / Mitogen-activated protein kinase kinase kinase kinase 1; / Hematopoietic progenitor kinase; / MAPK/ERK kinase kinase kinase 1; / MEK kinase kinase 1; / MEKKK 1
Species	Human
Gene ID	11184
Uniprot	Q92918,
Species.1	Mouse
Gene ID.1	26411
Uniprot.1	P70218
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	intracellular,cytoplasm,membrane,
Tissue Expression	Expressed primarily in hematopoietic organs, including bone marrow, spleen and thymus. Also expressed at very low levels in lung, kidney, mammary glands and small intestine.
Signaling_pathway	Environmental Information Processing >> Signal transduction >> MAPK signaling pathway
Research Areas	>>MAPK signaling pathway
Function	Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,Function:May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in hematopoietic lineage decisions and growth regulation.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 CNH domain.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with MAP3K1.,tissue specificity:Expressed primarily in hematopoietic organs, including bone marrow, spleen and thymus. Also expressed at very low levels in lung, kidney, mammary glands and small intestine.,

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HPK1 Polyclonal Antibody

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HPK1 Polyclonal Antibody

Product details

Specifications

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