Price range: $268.00 through $328.00
Background:
harakiri, BCL2 interacting protein(HRK) Homo sapiens This gene encodes a member of the BCL-2 protein family. Members of this family are involved in activating or inhibiting apoptosis. The encoded protein localizes to intracellular membranes. This protein promotes apoptosis by interacting with the apoptotic inhibitors BCL-2 and BCL-X(L) via its BH3 domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012],
| Size | 50μL/100μL |
| Target | HRK |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 10kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein AA range: 1-50 |
| Specificity | HRK Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | HRK BID3 |
| Protein Name | Activator of apoptosis harakiri (BH3-interacting domain-containing protein 3) (Neuronal death protein DP5) |
| Other Name | |
| Species | Human |
| Gene ID | 8739 |
| Uniprot | O00198, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P62816, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | P62817 |
| Cellular Localization | Membrane; Single-pass membrane protein. Mitochondrion. |
| Tissue Expression | |
| Signaling_pathway | Cellular Processes >> Cell growth and death >> Apoptosis |
| Research Areas | >>Apoptosis |
| Function | Domain:The BH3 motif is required for the induction of cell death.,Function:Activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-X(L)., |
