Product details
Background:
HSD17B3 rabbit pAb
Ucallm_WP6767-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | HSD17B3 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 34kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human HSD17B3 |
| Specificity | This antibody detects endogenous levels of HSD17B3 at Human, Mouse,Rat |
| Gene Name | HSD17B3 EDH17B3 |
| Protein Name | Testosterone 17-beta-dehydrogenase 3 (17-beta-hydroxysteroid dehydrogenase type 3) (17-beta-HSD 3) (Testicular 17-beta-hydroxysteroid dehydrogenase) |
| Other Name | |
| Species | Human |
| Gene ID | 3293 |
| Uniprot | P37058, |
| Species.1 | Mouse |
| Gene ID.1 | 15487 |
| Uniprot.1 | P70385, |
| Species.2 | Rat |
| Gene ID.2 | 117182 |
| Uniprot.2 | O54939 |
| Cellular Localization | Endoplasmic reticulum . |
| Tissue Expression | Testis. |
| Signaling_pathway | |
| Research Areas | |
| Function | Catalyzes the conversion of 17-oxosteroids to 17beta-hydroxysteroids . Favors the reduction of androstenedione to testosterone . Testosterone is the key androgen driving male development and function . Uses NADPH while the two other EDH17B enzymes use NADH . Androgens such as epiandrosterone, dehydroepiandrosterone, androsterone and androstanedione are accepted as substrates and reduced at C-17 . Can reduce 11-ketoandrostenedione as well as 11beta-hydroxyandrostenedione at C-17 to the respective testosterone forms . |
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