Price range: $268.00 through $328.00
Background:
heat shock transcription factor 2(HSF2) Homo sapiens The protein encoded by this gene belongs to the HSF family of transcription factors that bind specifically to the heat-shock promoter element and activate transcription. Heat shock transcription factors activate heat-shock response genes under conditions of heat or other stresses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011],
| Size | 50μL/100μL |
| Target | HSF2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 85kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human HSF2. AA range:401-450 |
| Specificity | HSF2 Polyclonal Antibody detects endogenous levels of HSF2 protein. |
| Gene Name | HSF2 |
| Protein Name | Heat shock factor protein 2 |
| Other Name | HSF2; / HSTF2; / Heat shock factor protein 2; / HSF 2; / Heat shock transcription factor 2; / HSTF 2 |
| Species | Human |
| Gene ID | 3298 |
| Uniprot | Q03933, |
| Species.1 | Mouse |
| Gene ID.1 | 15500 |
| Uniprot.1 | P38533 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . Nucleus . Cytoplasmic during normal growth and moves to the nucleus upon activation. |
| Tissue Expression | Bladder,Brain,PCR rescued clones,Testis, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.,similarity:Belongs to the HSF family.,subcellular location:Cytoplasmic during normal growth and moves to the nucleus upon activation.,subunit:DNA-binding homotrimer in stressed or heat shocked cells, otherwise found as a homodimer., |
