HXB8 Polyclonal Antibody
Ucallm_WP1203-50
Price range: $268.00 through $328.00
Product details
Background:
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | HXB8 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 26kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | HXB8 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | HOXB8 HOX2D |
| Protein Name | Homeobox protein Hox-B8 (Homeobox protein Hox-2.4) (Homeobox protein Hox-2D) |
| Other Name | |
| Species | Human |
| Gene ID | 3218 |
| Uniprot | P17481, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P09632, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | P18863 |
| Cellular Localization | Nucleus. |
| Tissue Expression | Placenta, |
| Signaling_pathway | |
| Research Areas | |
| Function | developmental stage:Expressed in whole embryos and fetuses at 5-9 weeks from conception.,Function:Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.,similarity:Belongs to the Antp homeobox family.,similarity:Contains 1 homeobox DNA-binding domain., |
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