Iba1 Polyclonal Antibody
Ucallm_WP2563-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T-lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full-length and coding nature of some of these variants is not certain. [provided by RefSeq, Jan 2016],
Specifications
| Size | 50μL/100μL |
| Target | AIF1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 16kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; ELISA 1:5000; IF 1:100-300; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | AIF1 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | AIF1 G1 IBA1 |
| Protein Name | Allograft inflammatory factor 1 (AIF-1) (Ionized calcium-binding adapter molecule 1) (Protein G1) |
| Other Name | |
| Species | Human |
| Gene ID | 199 |
| Uniprot | P55008, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | O70200, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | P55009 |
| Cellular Localization | Cytoplasm, cytoskeleton . Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side . Cell projection, phagocytic cup . Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis. . |
| Tissue Expression | Detected in T-lymphocytes and peripheral blood mononuclear cells. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:May play a role in macrophage activation and function.,PTM:Phosphorylated on serine residues.,similarity:Contains 2 EF-hand domains., |
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