Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human IER3IP1
Specificity
This antibody detects endogenous levels of IER3IP1 at Human, Mouse,Rat
Gene Name
IER3IP1 HSPC039
Protein Name
Immediate early response 3-interacting protein 1
Other Name
Species
Human
Gene ID
51124
Uniprot
Q9Y5U9,
Species.1
Mouse
Gene ID.1
66191
Uniprot.1
Q9CR20,
Species.2
Rat
Gene ID.2
Uniprot.2
P85007
Cellular Localization
Endoplasmic reticulum membrane; Multi-pass membrane protein .
Tissue Expression
Highest levels in heart, skeletal muscle, and kidney.
Signaling_pathway
Research Areas
Function
Regulator of endoplasmic reticulum secretion that acts as a key determinant of brain size . Required for secretion of extracellular matrix proteins . Required for correct brain development by depositing sufficient extracellular matrix proteins for tissue integrity and the proliferation of neural progenitors . Acts as a regulator of the unfolded protein response (UPR) (By similarity).