SKU: WP2040 Categories: ,

IFRD1 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP2040-100
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Product details

Background:

This gene is an immediate early gene that encodes a protein related to interferon-gamma. This protein may function as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration. Mutations in this gene are associated with sensory/motor neuropathy with ataxia. This gene may also be involved in modulating the pathogenesis of cystic fibrosis lung disease. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010],

Specifications

Size50μL/100μL
TargetIFRD1
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)49kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human protein . at AA range: 280-360
SpecificityIFRD1 Polyclonal Antibody detects endogenous levels of protein.
Gene NameIFRD1
Protein NameInterferon-related developmental regulator 1 (Nerve growth factor-inducible protein PC4)
Other Name
SpeciesHuman
Gene ID3475
UniprotO00458,
Species.1Mouse
Gene ID.1
Uniprot.1P19182,
Species.2Rat
Gene ID.2
Uniprot.2P20695
Cellular Localizationnucleus,cytoplasm,
Tissue ExpressionExpressed in a variety of tissues.
Signaling_pathway
Research Areas
FunctionFunction:Could play a role in regulating gene activity in the proliferative and/or differentiative pathways induced by NGF. May be an autocrine factor that attenuates or amplifies the initial ligand-induced signal.,similarity:Belongs to the IFRD family.,subunit:Interacts with PSIP1/LEDGF.,tissue specificity:Expressed in a variety of tissues.,
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