IFT140 rabbit pAb
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | IFT140 |
| Reactivity | Human |
| Applications | WB |
| MW(Calculated) | 161kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human IFT140 |
| Specificity | This antibody detects endogenous levels of IFT140 at Human |
| Gene Name | IFT140 KIAA0590 WDTC2 |
| Protein Name | Intraflagellar transport protein 140 homolog (WD and tetratricopeptide repeats protein 2) |
| Other Name | |
| Species | Human |
| Gene ID | 9742 |
| Uniprot | Q96RY7 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm, cytoskeleton, cilium basal body . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cell projection, cilium . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs) . Plays a pivotal role in proper development and function of ciliated cells through its role in ciliogenesis and/or cilium maintenance . Required for the development and maintenance of the outer segments of rod and cone photoreceptor cells. Plays a role in maintenance and the delivery of opsin to the outer segment of photoreceptor cells (By similarity). |
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