SKU: WP8335 Categories: ,

IKIP rabbit pAb

Price range: $268.00 through $328.00

SKU: WP8335-100
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Product details

Background:

Specifications

TargetIKBIP
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)39kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Modification
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human IKIP
Sequence
SpecificityThis antibody detects endogenous levels of IKIP at Human, Mouse,Rat
Gene NameIKBIP IKIP
Protein NameInhibitor of nuclear factor kappa-B kinase-interacting protein (I kappa-B kinase-interacting protein) (IKBKB-interacting protein) (IKK-interacting protein)
Other Name
SpeciesHuman
Gene ID-1121457
UniprotQ70UQ0,
Species.1Mouse
Gene ID-267454
Uniprot.1Q9DBZ1,
Species.2Rat
Gene ID-3314730
Uniprot.2Q5EAJ6
Organism-4
Gene ID-4
SwissProt-4
Background
Cellular LocalizationEndoplasmic reticulum membrane; Single-pass membrane protein . Isoform 4 deletion of the hydrophobic, or transmembrane region between AA 45-63 results in uniform distribution throughout the cell, suggesting that this region is responsible for endoplasmic reticulum localization.
Tissue ExpressionExpressed in vein endothelial cells. Isoform 4 is expressed in lung, kidney, spleen, thymus and skeletal muscle.
Signaling_pathway
Research Areas
FunctionTarget of p53/TP53 with pro-apoptotic function.
RRID
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