Name: IL28B Polyclonal Antibody
SKU: WP0656
Price: 268 USD
Availability: InStock

IL28B Polyclonal Antibody

Ucallm_WP0656-50

Price range: $268.00 through $328.00

Size

100μl

50μl

Clear

SKU: WP0656-100

Enter the quantity you would like, or drag the panel to find the quantity and price that best for you

Bulk Quote Authorize OEM & ODM

Product details

Background:

This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008],

Specifications

Target	IL28B
Reactivity	Human, Mouse
Applications	WB, ELISA
MW(Calculated)
MW(Observed)	21kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Modification
Recommended Dilution Ratio	WB 1:500-2000; ELISA 1:5000-20000
Formulation	Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Source
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	Synthesized peptide derived from human protein . at AA range: 100-180
Sequence
Specificity	IL28B Polyclonal Antibody detects endogenous levels of protein.
Gene Name	IL28B IFNL3 IFNL4 IL28C ZCYTO22
Protein Name	Interleukin-28B (IL-28B) (Cytokine Zcyto22) (Interferon lambda-3) (IFN-lambda-3) (Interferon lambda-4) (IFN-lambda-4) (Interleukin-28C) (IL-28C)
Other Name
Species	Human
Gene ID-1	282617
Uniprot	Q8IZI9,
Species.1	Mouse
Gene ID-2
Uniprot.1	Q8CGK6
Species.2
Gene ID-3
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
Background	This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008],
Cellular Localization	Secreted .
Tissue Expression	Pooled,
Signaling_pathway	Environmental Information Processing >> Signal transduction >> JAK-STAT signaling pathway;Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction
Research Areas	>>Cytokine-cytokine receptor interaction; / >>JAK-STAT signaling pathway
Function	Caution:It is uncertain whether Met-1 or Met-5 is the initiator.,Function:Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.,induction:By viral infections or double stranded RNA.,similarity:Belongs to the IL-28/IL-29 family.,
RRID

Please login to post questions

IL28B Polyclonal Antibody

Product details

Specifications

About Us

Support

Order

Menu

IL28B Polyclonal Antibody

Product details

Specifications

Related products

U-Blot® Ezrin Rabbit mAb

U-Blot® α smooth muscle actin Rabbit mAb

U-Blot® FOXO3A (Phospho Ser253) Rabbit mAb

U-Blot® Smad2 (Phospho Ser250) Rabbit mAb

U-Blot® MMP7 Rabbit mAb

Acetyl Lysine Monoclonal Antibody [10B10]

Customer Reviews

Menu