IMA8 rabbit pAb
Ucallm_WP16766-50
Price range: $268.00 through $328.00
Product details
Background:
The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import, but exhibits different nuclear localization signal binding specificity compared to other members of the family. A pseudogene of this gene has been defined on chromosome 5. [provided by RefSeq, Jul 2016],
Specifications
| Size | 50μL/100μL |
| Target | IMA8 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 57kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human IMA8 AA range: 313-363 |
| Specificity | This antibody detects endogenous levels of IMA8 at Human/Mouse |
| Gene Name | KPNA7 |
| Protein Name | IMA8 |
| Other Name | |
| Species | Human |
| Gene ID | 402569 |
| Uniprot | A9QM74, |
| Species.1 | Mouse |
| Gene ID.1 | 381686 |
| Uniprot.1 | C0LLJ0 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | |
| Signaling_pathway | Genetic Information Processing >> Translation >> Nucleocytoplasmic transport |
| Research Areas | >>Nucleocytoplasmic transport; / >>Influenza A; / >>Chemical carcinogenesis - receptor activation |
| Function | Function:Functions in nuclear protein import.,similarity:Belongs to the importin alpha family.,similarity:Contains 1 IBB domain.,similarity:Contains 8 ARM repeats., |
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