IMPCT rabbit pAb
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | IMPCT |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 35kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human IMPCT AA range: 123-173 |
| Specificity | This antibody detects endogenous levels of IMPCT at Human/Mouse/Rat |
| Gene Name | IMPACT |
| Protein Name | IMPCT |
| Other Name | |
| Species | Human |
| Gene ID | 55364 |
| Uniprot | Q9P2X3, |
| Species.1 | Mouse |
| Gene ID.1 | 16210 |
| Uniprot.1 | O55091, |
| Species.2 | Rat |
| Gene ID.2 | 497198 |
| Uniprot.2 | Q5GFD9 |
| Cellular Localization | Cytoplasm . |
| Tissue Expression | Widely expressed. Expressed at high level in brain. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Translational regulator that ensures constant high levels of translation under amino acid starvation. Acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis.,miscellaneous:In contrast to the mouse or rabbit ortholog, the IMPACT locus is not imprinted in human.,similarity:Belongs to the IMPACT family.,similarity:Contains 1 RWD domain.,subunit:Interacts with GCN1/GCN1L1.,tissue specificity:Widely expressed. Expressed at high level in brain., |
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