Name: Inhibin β-A Polyclonal Antibody
SKU: WP15451
Price: 268 USD
Availability: InStock

Inhibin β-A Polyclonal Antibody

Ucallm_WP15451-50

Price range: $268.00 through $328.00

Size

100μl

50μl

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SKU: WP15451-100

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Product details

Background:

This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. The encoded protein also plays a role in eye, tooth and testis development. Elevated expression of this gene may be associated with cancer cachexia in human patients. [provided by RefSeq, Aug 2016],

Specifications

Size	50μL/100μL
Target	Inhibin β-A
Reactivity	Human, Mouse, Rat
Applications	WB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)	52kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-1:2000; IHC: 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	The antiserum was produced against synthesized peptide derived from the C-terminal region of human INHBA. AA range:377-426
Specificity	Inhibin β-A Polyclonal Antibody detects endogenous levels of Inhibin β-A protein.
Gene Name	INHBA
Protein Name	Inhibin beta A chain
Other Name	INHBA; / Inhibin beta A chain; / Activin beta-A chain; / Erythroid differentiation protein; / EDF
Species	Human
Gene ID	3624
Uniprot	P08476,
Species.1	Mouse
Gene ID.1	16323
Uniprot.1	Q04998,
Species.2	Rat
Gene ID.2	29200
Uniprot.2	P18331
Cellular Localization	Secreted.
Tissue Expression	Dermoid cancer,Eye,Fetal brain,Testis,
Signaling_pathway	Cellular Processes >> Cellular community - eukaryotes >> Signaling pathways regulating pluripotency of stem cells;Environmental Information Processing >> Signal transduction >> TGF-beta signaling pathway;Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction
Research Areas	>>Cytokine-cytokine receptor interaction; / >>TGF-beta signaling pathway; / >>Signaling pathways regulating pluripotency of stem cells
Function	Function:Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.,online information:Activin entry,similarity:Belongs to the TGF-beta family.,subunit:Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B. Activin A is a homodimer of beta-A. Activin B is a homodimer of beta-B. Activin AB is a dimer of beta-A and beta-B.,

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Inhibin β-A Polyclonal Antibody

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Inhibin β-A Polyclonal Antibody

Product details

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