INT11 rabbit pAb
Ucallm_WP8034-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | INTS11 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 66kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human INT11 |
| Specificity | This antibody detects endogenous levels of INT11 at Human, Mouse,Rat |
| Gene Name | CPSF3L INTS11 RC68 |
| Protein Name | Integrator complex subunit 11 (Int11) (Cleavage and polyadenylation-specific factor 3-like protein) (CPSF3-like protein) (Protein related to CPSF subunits of 68 kDa) (RC-68) |
| Other Name | |
| Species | Human |
| Gene ID | 54973 |
| Uniprot | Q5TA45, |
| Species.1 | Mouse |
| Gene ID.1 | 71957 |
| Uniprot.1 | Q9CWS4, |
| Species.2 | Rat |
| Gene ID.2 | 298688 |
| Uniprot.2 | Q3MHC2 |
| Cellular Localization | Nucleus . Cytoplasm . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Catalytic component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates the snRNAs 3' cleavage. Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex . |
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