IP6K2 Polyclonal Antibody
Ucallm_WP12857-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1, 3, 4, 5, 6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | IP6K2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 49kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human IP6K2. AA range:161-210 |
| Specificity | IP6K2 Polyclonal Antibody detects endogenous levels of IP6K2 protein. |
| Gene Name | IP6K2 |
| Protein Name | Inositol hexakisphosphate kinase 2 |
| Other Name | IP6K2; / IHPK2; / TCCCIA00113; / Inositol hexakisphosphate kinase 2; / InsP6 kinase 2; / P; / i; / -uptake stimulator; / PiUS |
| Species | Human |
| Gene ID | 51447 |
| Uniprot | Q9UHH9, |
| Species.1 | Mouse |
| Gene ID.1 | 76500 |
| Uniprot.1 | Q80V72, |
| Species.2 | Rat |
| Gene ID.2 | 59268 |
| Uniprot.2 | Q9R0U1 |
| Cellular Localization | Nucleus . |
| Tissue Expression | Caudate nucleus,Glial tumor,Leukemia,Lung,Skin,Uterus, |
| Signaling_pathway | |
| Research Areas | >>Phosphatidylinositol signaling system |
| Function | Catalytic activity:ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + diphospho-1D-myo-inositol tetrakisphosphate (isomeric configuration unknown).,Catalytic activity:ATP + 1D-myo-inositol hexakisphosphate = ADP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate.,Function:Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4.,similarity:Belongs to the inositol phosphokinase (IPK) family., |
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