Price range: $268.00 through $328.00
Background:
This gene encodes a member of a family of large proteins containing PHD (plant homeo domain)-type zinc fingers. The encoded protein may be associated in a nuclear complex that functions in histone H4 acetylation. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2013],
| Size | 50μL/100μL |
| Target | JADE3 |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| MW(Calculated) | 91kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; IHC 1:50-300 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human JADE3 AA range: 484-534 |
| Specificity | This antibody detects endogenous levels of JADE3 at Human/Mouse |
| Gene Name | PHF16 JADE3 KIAA0215 |
| Protein Name | JADE3 |
| Other Name | |
| Species | Human |
| Gene ID | 9767 |
| Uniprot | Q92613, |
| Species.1 | Mouse |
| Gene ID.1 | 382207 |
| Uniprot.1 | Q6IE82 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | histone acetyltransferase complex, |
| Tissue Expression | Ubiquitously expressed, with highest levels in placenta and uterus. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo.,induction:By estradiol in estrogen-responsive breast cancer cells.,similarity:Belongs to the JADE family.,similarity:Contains 1 PHD-type zinc finger.,subunit:Component of the HBO1 complex composed at least of ING4 or ING5, MYTS2/HBO1, EAF6, and one of PHF15, PHF16 and PHF17.,tissue specificity:Ubiquitously expressed, with highest levels in placenta and uterus., |
