SKU: WP6959 Categories: ,

JAKMIP1 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP6959-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetJAKMIP1
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)69kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human JAKMIP1
SpecificityThis antibody detects endogenous levels of JAKMIP1 at Human, Mouse,Rat
Gene NameJAKMIP1 GABABRBP JAMIP1 MARLIN1
Protein NameJanus kinase and microtubule-interacting protein 1 (GABA-B receptor-binding protein) (Multiple alpha-helices and RNA-linker protein 1) (Marlin-1)
Other Name
SpeciesHuman
Gene ID152789
UniprotQ96N16,
Species.1Mouse
Gene ID.176071
Uniprot.1Q8BVL9,
Species.2Rat
Gene ID.2305434
Uniprot.2Q3SWS9
Cellular LocalizationCytoplasm, cytoskeleton. Membrane; Peripheral membrane protein. Colocalizes with the microtubule network. Localizes to the cell body and neurites of hippocampal neurons where it accumulates in granules. Localizes to the tail and to a lower extent to the head of sperm cells.
Tissue ExpressionPredominantly expressed in neural tissues and lymphoid cells (at protein level). Isoform 2, isoform 3 and isoform 4 are specifically expressed in brain and retina. Isoform 1 and isoform 5 are also detected in liver, lung and skeletal muscle. Also detected in testis and to a lower extent spleen and intestine.
Signaling_pathway
Research Areas
FunctionAssociates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements.
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