Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human JAKMIP1
Specificity
This antibody detects endogenous levels of JAKMIP1 at Human, Mouse,Rat
Gene Name
JAKMIP1 GABABRBP JAMIP1 MARLIN1
Protein Name
Janus kinase and microtubule-interacting protein 1 (GABA-B receptor-binding protein) (Multiple alpha-helices and RNA-linker protein 1) (Marlin-1)
Other Name
Species
Human
Gene ID
152789
Uniprot
Q96N16,
Species.1
Mouse
Gene ID.1
76071
Uniprot.1
Q8BVL9,
Species.2
Rat
Gene ID.2
305434
Uniprot.2
Q3SWS9
Cellular Localization
Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein. Colocalizes with the microtubule network. Localizes to the cell body and neurites of hippocampal neurons where it accumulates in granules. Localizes to the tail and to a lower extent to the head of sperm cells.
Tissue Expression
Predominantly expressed in neural tissues and lymphoid cells (at protein level). Isoform 2, isoform 3 and isoform 4 are specifically expressed in brain and retina. Isoform 1 and isoform 5 are also detected in liver, lung and skeletal muscle. Also detected in testis and to a lower extent spleen and intestine.
Signaling_pathway
Research Areas
Function
Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements.