SKU: WP0669 Categories: ,

K1C23 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP0669-100
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Product details

Background:

The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],

Specifications

Size50μL/100μL
TargetK1C23
ReactivityHuman, Mouse
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)46kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human protein . at AA range: 150-230
SpecificityK1C23 Polyclonal Antibody detects endogenous levels of protein.
Gene NameKRT23
Protein NameKeratin, type I cytoskeletal 23 (Cytokeratin-23) (CK-23) (Keratin-23) (K23)
Other Name
SpeciesHuman
Gene ID25984
UniprotQ9C075,
Species.1Mouse
Gene ID.1
Uniprot.1Q99PS0
Species.2
Gene ID.2
Uniprot.2
Cellular Localizationintermediate filament,
Tissue ExpressionPlacenta,Testis,Urinary bladder,
Signaling_pathwayOrganismal Systems >> Endocrine system >> Estrogen signaling pathway
Research Areas>>Estrogen signaling pathway; / >>Staphylococcus aureus infection
Functionmiscellaneous:There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).,similarity:Belongs to the intermediate filament family.,subunit:Heterotetramer of two type I and two type II keratins.,
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