Kallikrein-7 (Cleaved-Ile30) rabbit pAb
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | Kallikrein-7 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| MW(Calculated) | |
| MW(Observed) | 25kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; IHC 1:50-300 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human Kallikrein-7 (Cleaved-Ile30) |
| Specificity | This antibody detects endogenous levels of Human,Mouse,Rat Kallikrein-7 (Cleaved-Ile30, protein was cleaved amino acid sequence between 29-30 ) |
| Gene Name | KLK7 PRSS6 SCCE |
| Protein Name | Kallikrein-7 (Cleaved-Ile30) |
| Other Name | Kallikrein-7; / hK7; / Serine protease 6; / Stratum corneum chymotryptic enzyme; / hSCCE |
| Species | Human |
| Gene ID | 5650 |
| Uniprot | P49862, |
| Species.1 | Mouse |
| Gene ID.1 | 23993 |
| Uniprot.1 | Q91VE3, |
| Species.2 | Rat |
| Gene ID.2 | 24523 |
| Uniprot.2 | P36373 |
| Cellular Localization | Secreted . In ovarian carcinoma, secreted and also observed at the apical membrane and in cytoplasm at the invasive front. |
| Tissue Expression | Abundantly expressed in the skin and is expressed by keratinocytes in the epidermis. Also expressed in the brain, mammary gland, cerebellum, spinal cord and kidney. Lower levels in salivary glands, uterus, thymus, thyroid, placenta, trachea and testis. Up-regulated in ovarian carcinoma, especially late-stage serous carcinoma, compared with normal ovaries and benign adenomas (at protein level). |
| Signaling_pathway | |
| Research Areas | |
| Function |
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