Kanadaptin Polyclonal Antibody
Product details
Background:
caution:PubMed:15764369 initially suggested a role in targeting SLC4A1 (kidney anion exchanger 1) to the plasma membrane; it does not seem to do so as it does not interact with SLC4A1 and has no effect on SLC4A1 trafficking., online information:Band 3 entry, PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Contains 1 FHA domain., subcellular location:Mainly nuclear. Small amounts are found in the cytoplasm., tissue specificity:Ubiquitously expressed.,
Specifications
| Size | 50μL/100μL |
| Target | Kanadaptin |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 85kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human NADAP. AA range:421-470 |
| Specificity | Kanadaptin Polyclonal Antibody detects endogenous levels of Kanadaptin protein. |
| Gene Name | SLC4A1AP |
| Protein Name | Kanadaptin |
| Other Name | SLC4A1AP; / HLC3; / Kanadaptin; / Human lung cancer oncogene 3 protein; / HLC-3; / Kidney anion exchanger adapter protein; / Solute carrier family 4 anion exchanger member 1 adapter protein |
| Species | Human |
| Gene ID | 22950 |
| Uniprot | Q9BWU0 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . Cytoplasm . Mainly nuclear. Small amounts are found in the cytoplasm. |
| Tissue Expression | Ubiquitously expressed. |
| Signaling_pathway | |
| Research Areas | |
| Function | Caution:PubMed:15764369 initially suggested a role in targeting SLC4A1 (kidney anion exchanger 1) to the plasma membrane; it does not seem to do so as it does not interact with SLC4A1 and has no effect on SLC4A1 trafficking.,online information:Band 3 entry,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 FHA domain.,subcellular location:Mainly nuclear. Small amounts are found in the cytoplasm.,tissue specificity:Ubiquitously expressed., |
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