Price range: $268.00 through $328.00
Background:
This gene encodes a member of a family of serine/threonine protein kinases that phosphorylate caseins and other acidic proteins. A related protein in the African clawed frog participates in the transmission of Wnt/beta-catenin signaling. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012],
| Size | 50μL/100μL |
| Target | KC1G3 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 49kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | KC1G3 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | CSNK1G3 |
| Protein Name | Casein kinase I isoform gamma-3 (CKI-gamma 3) (EC 2.7.11.1) |
| Other Name | |
| Species | Human |
| Gene ID | 1456 |
| Uniprot | Q9Y6M4, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q8C4X2, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | Q62763 |
| Cellular Localization | Cytoplasm. |
| Tissue Expression | Brain,Testis, |
| Signaling_pathway | Environmental Information Processing >> Signal transduction >> Hedgehog signaling pathway |
| Research Areas | >>Hedgehog signaling pathway |
| Function | Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,Function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling.,miscellaneous:Triazolodiamine 1 is a commercial name for 5-amino-3-([4-(aminosulfonyl)phenyl]amino)-N-(2,6-difluorophenyl)-1H-1,2,4-triazole-1-carbothioamide.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer., |
