Product details
Background:
KCC4/SLC12A7 rabbit pAb
Ucallm_WP7940-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | SLC12A7 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 119kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human KCC4/SLC12A7 |
| Specificity | This antibody detects endogenous levels of KCC4/SLC12A7 at Human, Mouse,Rat |
| Gene Name | SLC12A7 KCC4 |
| Protein Name | Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4) |
| Other Name | |
| Species | Human |
| Gene ID | 10723 |
| Uniprot | Q9Y666, |
| Species.1 | Mouse |
| Gene ID.1 | 20499 |
| Uniprot.1 | Q9WVL3, |
| Species.2 | Rat |
| Gene ID.2 | 308069 |
| Uniprot.2 | Q5RK27 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. |
| Tissue Expression | Detected in muscle, brain, lung, heart and kidney. |
| Signaling_pathway | |
| Research Areas | |
| Function | Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification (By similarity). |
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