SKU: WP7278 Categories: ,

KCNQ3 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP7278-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetKCNQ3
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)96kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human KCNQ3
SpecificityThis antibody detects endogenous levels of KCNQ3 at Human, Mouse,Rat
Gene NameKCNQ3
Protein NamePotassium voltage-gated channel subfamily KQT member 3 (KQT-like 3) (Potassium channel subunit alpha KvLQT3) (Voltage-gated potassium channel subunit Kv7.3)
Other Name
SpeciesHuman
Gene ID3786
UniprotO43525,
Species.1Mouse
Gene ID.1110862
Uniprot.1Q8K3F6,
Species.2Rat
Gene ID.229682
Uniprot.2O88944
Cellular LocalizationCell membrane; Multi-pass membrane protein .
Tissue ExpressionPredominantly expressed in brain.
Signaling_pathwayOrganismal Systems >> Nervous system >> Cholinergic synapse
Research Areas
FunctionAssociates with KCNQ2 or KCNQ5 to form a potassium channel with essentially identical properties to the channel underlying the native M-current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons as well as the responsiveness to synaptic inputs. Therefore, it is important in the regulation of neuronal excitability.
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