Keratin 37/38 Polyclonal Antibody
Ucallm_WP12915-50
Price range: $268.00 through $328.00
Product details
Background:
The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | Keratin 37/38 |
| Reactivity | Human |
| Applications | WB, ELISA, IHC |
| MW(Calculated) | |
| MW(Observed) | 50kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human KRT37/38. AA range:201-250 |
| Specificity | Keratin 37/38 Polyclonal Antibody detects endogenous levels of Keratin 37/38 protein. |
| Gene Name | KRT37/KRT38 |
| Protein Name | Keratin type I cuticular Ha7/Keratin type I cuticular Ha8 |
| Other Name | KRT37; / HHA7; / HKA7; / KRTHA7; / Keratin; / type I cuticular Ha7; / Hair keratin, type I Ha7; / Keratin-37; / K37; / KRT38; / HHA8; / HKA8; / KRTHA8; / Keratin, type I cuticular Ha8; / Hair keratin, type I Ha8; / Keratin-38; / K38 |
| Species | Human |
| Gene ID | 8688 |
| Uniprot | O76014;O76015 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | intermediate filament,extracellular exosome, |
| Tissue Expression | Scalp, |
| Signaling_pathway | Organismal Systems >> Endocrine system >> Estrogen signaling pathway |
| Research Areas | >>Estrogen signaling pathway; / >>Staphylococcus aureus infection |
| Function | miscellaneous:There are two types of hair/microfibrillar keratin, I (acidic) and II (neutral to basic).,similarity:Belongs to the intermediate filament family., |
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